Centers for Mendelian Genomics

The Centers for Mendelian Genomics (CMG) use genome-wide sequencing and other genomic approaches to discover the genetic basis underlying as many Mendelian traits as possible, and accelerate discoveries by disseminating the obtained knowledge and effective approaches, reaching out to individual investigators, and coordinating with other rare disease programs worldwide.

The currently funded CMG are: the Baylor-Hopkins CMG, the Broad Institute CMG, the University of Washington CMG, and the Yale University CMG. Please direct inquiries about collaborations directly to the centers.

The CMGs contribute to the overall field of Mendelian genetics which has been responsible for many disease gene discoveries. For more information see the detailed Mendelian Traits by the Numbers report and the list of phenotypes studied, and disease genes identified, by the CMGs. See the detailed  for more information.

CMG Review Papers

Upcoming Meetings

Wellcome Genome Campus, Hinxton, Cambridge, UK, April 5-7,  2017.

Third International Rare Diseases Research Consortium (IRDiRC) conference.
Paris, France, February 8-9, 2017.


Learn more about the NHGRI Centers for Mendelian Genetics Program.

Date Last Modified: Tue, 02/07/2017 - 11:13